I've taken magic mushrooms on multiple occasions as well as identical substances like 4-AcO-DMT (psilacetin), all of which have resulted in extremely uncomfortable "bad" trips. Not scary or anxiety-producing, just depressing & unpleasant as if I'm dying but without any fear attached. My friends would be laughing & having a grand time while I'd be curled up in the fetal position praying for it to stop. But the afterglow always felt refreshing, as if I'd just come back from some kind of mental vacation or hit a spiritual "reset" button. This feeling of invigoration lasted a couple days at most before my old grey cloud came back. This is how all drugs tend to work with me.
Anyhow, it's interesting seeing how psilocybin affects the 3 men in the study, all of whom are severely depressed. The outcomes are not what you expect. The first dose is a small threshold dose while the second is a larger 2.5 gram equivalent dose that produces more profound effects. From that alone, significant results are seen. Here's the documentary:
Do you think it's safe to give psilocybin to severely depressed patients? Got any experiences you'd like to share? Leave a comment below & get the conversation going. This is likely to be a big issue in the psychiatric field in the coming decade as attitudes toward psychedelics change.