*70q0 is the probability of dying before age 70.
The Global Burden of Disease Study is the most comprehensive global death probability calculation estimate in the world. It's published in The Lancet every few years and is extensively researched and meticulous. You can read the whole thing here. It includes not only health-related causes of death but all other causes as well (accidental injury, war/terrorism, extreme weather, suicide, etc).
From 1990 to 2023, ischaemic heart disease and stroke consistently ranked as the first and second leading causes, respectively—except in 2021, when COVID-19 temporarily ranked as the leading cause of age-standardised deaths.
Here are Top 20 killers in various years:

Click to enlarge
First, the good news. The global all-cause age at death increased from 46.8 years in 1990 to 63.4 years in 2023. The global reduction in dying before age 70 due to tuberculosis from 2000 to 2023 is a success story. There was an overall decline of 60·0% in females and 58·0% in males. Lower respiratory infections declined 51.2% among females and 47.4% among males between 2000 and 2023 due to reductions in various risk factors, including reductions in household air pollution, a decrease in the prevalence of childhood wasting, and improved vaccine coverage. Global improvements were also observed in diarrheal diseases, with declines of over 70% for males and females.
Over the past three decades, there were large improvements in life expectancy where four causes of death were concerned: respiratory infections and tuberculosis, nutritional deficiencies, other infectious diseases, and enteric infections—which had individual declines ranging from 58.9% to 79.0%. This achievement was facilitated by many years of sustained international cooperation with local governments.
Now the not-so-good: 70q0 due to drug use disorders increased by 56.8% in males and 68.0% in females globally. Between 2020 and 2023, COVID-19 had an immense global impact, resulting in 18 million total deaths. Among these, 10·5 million deaths were in males, and 7·53 million (6·98–7·96) deaths were in females.
Differences between the sexes didn't end there. Among the top 50 global causes of death for females, the 15 with the largest increase in 70q0 between 2000 and 2023 were (in decreasing order):
interstitial lung disease and pulmonary sarcoidosis;
drug use disorders;
lip and oral cavity cancer,
atrial fibrillation and flutter;
Alzheimer's disease and other dementias;
diabetes;
hypertensive heart disease;
pancreatic cancer;
Parkinson's disease;
ovarian cancer
other cardiovascular and circulatory diseases;
breast cancer;
endocrine, metabolic, blood, and immune disorders (+29·9%; 0·1%);
chronic kidney disease (+27·7%; 0·6%);
and non-rheumatic valvular heart disease
For males, the 15 causes of death with the largest increase in chance of dying before age 70 included (in decreasing order):
diabetes
drug use disorders
AFIB and flutter
Interstitial lung disease & pulmonary sarcoidosis
Alzheimer's and other dementias
Parkinson's disease
endocrine, metabolic, blood, and immune disorders
pancreatic cancer
lip and oral cavity cancer
prostate cancer
non-rheumatic valvular heart disease
chronic kidney disease
colon and rectum cancer
urinary diseases and male infertility
other cardiovascular and circulatory diseases
Ten countries had an increase in overall chance of dying before age 70. The largest was in Palestine (33.1% increase), more than double that of the next-largest increase in Lebanon with 15.3%. The staggering increase in Palestine is driven almost entirely by the conflict between Israel and Palestine, with an increase in 70q0 of 8980% due to conflict and terrorism. Within the first year of the war, Palestinians lost an estimated 30 years of life expectancy.
2026 and Beyond
What's in store for the next 10 years? Nobody knows, but things aren't looking rosy in the U.S. I stumbled upon this study while looking into the Lancet's recent article on RFK, Jr. It's startling in its candidness and pulls no punches about how disastrous this administration has been to our already ailing healthcare system. Here's a little snippet:
Full article here. This is one of, if not THEE most respected peer-reviewed medical journal in the world. Med journals aren't known for getting involved in politics, so this is truly troubling.
Endgame
My theory is that, after seeing the way COVID-19 enriched so many of the top 1%, turning billionaires to centibillionaires for the first time in history, the U.S. government would love to unleash another pandemic on the public to aid in the further upward transfer of wealth to the donor class. Who cares if we kill off a huge chunk of our own population? We can just import more work-age adults from South America and Mexico (Democrat strategy), or do away with child labor laws (Republican strategy). Heck, why not do away with those pesky labor laws altogether? Not like most employers abide by them anyway.
Sure, this also happens to be the anti-science crowd, but simply distrusting science and "mainstream" medicine is not an adequate explanation for the aggressiveness with which the government has done such severe harm to our already struggling public healthcare system. There's only so much $$$ you can make pushing detox supplements and other alternative medicine horseshit. This reeks of something more sinister.
Endgame
My theory is that, after seeing the way COVID-19 enriched so many of the top 1%, turning billionaires to centibillionaires for the first time in history, the U.S. government would love to unleash another pandemic on the public to aid in the further upward transfer of wealth to the donor class. Who cares if we kill off a huge chunk of our own population? We can just import more work-age adults from South America and Mexico (Democrat strategy), or do away with child labor laws (Republican strategy). Heck, why not do away with those pesky labor laws altogether? Not like most employers abide by them anyway.
Sure, this also happens to be the anti-science crowd, but simply distrusting science and "mainstream" medicine is not an adequate explanation for the aggressiveness with which the government has done such severe harm to our already struggling public healthcare system. There's only so much $$$ you can make pushing detox supplements and other alternative medicine horseshit. This reeks of something more sinister.
Once billionaires have stolen ALL the money in circulation, then they'll make poverty/homelessness a crime in all 50 states & incarcerate more people to get more free labor in our prisons. Who needs healthcare when you've got 3 hots and a cot? The new pandemic will kill off another million or so elderly, sick and feeble Americans so only the "good breeding stock" with "good genes" are left behind, simultaneously purging Social Security and the social welfare system of millions more poor and disabled people. Think of it as a Jonestown Massacre for the 21st Century. Then Elon and Bezos can race to Mars to determine ownership of the red planet, blasting off in their slavery-funded rocketships and leaving us all behind in waist-deep boiling sludge to fight over Earth's remaining resources.
Whew, that spiraled quickly. But we must assume these despots have an endgame in mind when they make sweeping cuts to our already ailing public healthcare infrastructure, fire scientists, reduce childhood vaccine recommendations/requirements and other shit that's 100% certain to trigger another mass wave of death that could make COVID look like the a head cold by comparison. Ignorance alone doesn't explain such aggressive--and aggressively stupid--behavior. Things that a literal retard could see are a bad idea if preserving human life is the goal (it's not). At a certain point you've got to assume malice.
What I wouldn't give to be a fly on the wall at Trump's secret cabinet meetings; to read their communications like we're now reading Epstein's emails. I can guarantee terms like "apocalypse insurance," "Great Replacement" and "social murder" are littered throughout.
Whew, that spiraled quickly. But we must assume these despots have an endgame in mind when they make sweeping cuts to our already ailing public healthcare infrastructure, fire scientists, reduce childhood vaccine recommendations/requirements and other shit that's 100% certain to trigger another mass wave of death that could make COVID look like the a head cold by comparison. Ignorance alone doesn't explain such aggressive--and aggressively stupid--behavior. Things that a literal retard could see are a bad idea if preserving human life is the goal (it's not). At a certain point you've got to assume malice.
What I wouldn't give to be a fly on the wall at Trump's secret cabinet meetings; to read their communications like we're now reading Epstein's emails. I can guarantee terms like "apocalypse insurance," "Great Replacement" and "social murder" are littered throughout.
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